Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00564Dabigatran etexilate--
BADD_D00566Dabrafenib0.002664%
BADD_D00567Dabrafenib mesylate--
BADD_D00574Dalfampridine--
BADD_D00578Dapagliflozin--
BADD_D00580Dapsone0.004810%
BADD_D00581Daptomycin0.001916%
BADD_D00582Daratumumab--
BADD_D00583Darbepoetin alfa--
BADD_D00585Darifenacin hydrobromide--
BADD_D00586Darunavir--
BADD_D00588Dasabuvir--
BADD_D00589Dasatinib0.021313%
BADD_D00590Daunorubicin--
BADD_D00591Daunorubicin citrate--
BADD_D00593Decitabine--
BADD_D00594Deferasirox--
BADD_D00596Deferoxamine0.005831%
BADD_D00602Delamanid--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00607Denileukin diftitox--
BADD_D00611Desflurane--
BADD_D00615Desloratadine0.007930%
BADD_D00616Desmopressin--
BADD_D00619Desonide--
BADD_D00621Desvenlafaxine--
BADD_D00623Dexamethasone--
BADD_D00628Dexlansoprazole0.002116%
BADD_D00629Dexmedetomidine--
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